One light, a few white spheres without a texture and a little bit rigid body simulation. After our trial period of Cinema4D has ran out, we tried to achieve some comparable results in Blender.
For now, it is way more limited and the performance in Cinema4D is really impressive, but with some tricks, you can achieve some great results in Blender as well.
When it comes to art direction, the task is getting more complicated (what would we do, if Blender would have something comparable to fields 😉 ), you need to create many helper objects and force fields, to restrict/control the rigid body behavior.